The Journal of Pediatrics
Volume 150, Issue 1 , Pages 18-25 , January 2007

Childhood Overweight and Cardiovascular Disease Risk Factors: The National Heart, Lung, and Blood Institute Growth and Health Study

Received 17 May 2006 ,Revised 29 July 2006 ,Accepted 23 September 2006.

References 

  1. Ogden CL, Flegal KM, Carroll MD, Johnson CL. Prevalence and trends in overweight among US children and adolescents, 1999-2000. JAMA. 2002;288:1728–1732
  2. Hedley AA, Ogden CL, Johnson CL, Carroll MD, Curtin LR, Flegal KM. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA. 2004;291:2847–2850
  3. Clarke WR, Woolson RF, Lauer RM. Changes in ponderosity and blood pressure in childhood: the Muscatine Study. Am J Epidemiol. 1986;124:195–206
  4. Gidding SS, Bao W, Srinivasan SR, Berenson GS. Effects of secular trends in obesity on coronary risk factors in children: the Bogalusa Heart Study. J Pediatr. 1995;127:868–874
  5. Freedman DS, Dietz WH, Srinivasan SR, Berenson GS. The relation of overweight to cardiovascular risk factors among children and adolescents: the Bogalusa Heart Study. Pediatrics. 1999;103:1175–1182
  6. Srinivasan SR, Myers L, Berenson GS. Temporal association between obesity and hyperinsulinemia in children, adolescents, and young adults: the Bogalusa Heart Study. Metabolism. 1999;48:928–934
  7. Srinivasan SR, Myers L, Berenson GS. Distribution and correlates of non–high-density lipoprotein cholesterol in children: the Bogalusa Heart Study. Pediatrics. 2002;110:e29
  8. Obarzanek E. Obesity in children, adolescents, and families. In:  Fletcher GF,  Grundy SM,  Hayman LL editor. Obesity: impact on cardiovascular disease. Armonk, NY: Futura; 1999;p. 31–53
  9. Steinberger J, Moran A, Hong CP, Jacobs DR, Sinaiko AR. Adiposity in childhood predicts obesity and insulin resistance in young adulthood. J Pediatr. 2001;138:469–473
  10. Guo SS, Wu W, Chumlea WC, Roche AF. Predicting overweight and obesity in adulthood from body mass index values in childhood and adolescence. Am J Clin Nutr. 2002;76:653–658
  11. Freedman DS, Khan LK, Serdula MK, Dietz WH, Srinivasan SR, Berenson GS. Inter-relationships among childhood BMI, childhood height, and adult obesity: the Bogalusa Heart Study. Int J Obes. 2004;28:10–16
  12. Freedman DS, Khan LK, Dietz WH, Srinivasan SR, Berenson GS. Relationship of childhood obesity to coronary heart disease risk factors in adulthood: the Bogalusa Heart Study. Pediatrics. 2001;108:712–718
  13. Himes J, Dietz W. Guidelines for overweight in adolescent preventive services: recommendations from an expert committee. Am J Clin Nutr. 1994;59:307–316
  14. Dietz WH, Robinson TN. Overweight children and adolescents. N Engl J Med. 2005;352:2100–2109
  15. Pietrobelli A, Faith MS, Allison DB, Gallagher D, Chiumello G, Heymsfield SB. Body mass index as a measure of adiposity among children and adolescents: a validation study. J Pediatr. 1998;132:204–210
  16. Frontini MG, Bao W, Elkasabany A, Srinivasan SR, Berenson G. Comparison of weight-for-height indices as a measure of adiposity and cardiovascular risk from childhood to young adulthood: the Bogalusa Heart Study. J Clin Epidemiol. 2001;54:817–822
  17. Bedogni G, Iughetti L, Ferrari M, Malavolti M, Poli M, Bernasconi S, et al. Sensitivity and specificity of body mass index and skinfold thicknesses in detecting excess adiposity in children aged 8-12 years. Ann Human Biol. 2003;30:132–139
  18. Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey clinical growth charts. Available at http://www.cdc.gov/nchs/about/major/nhanes/growthcharts/clinical_charts.htm. Accessed October 18, 2006.
  19. National Heart, Lung, and Blood Institute Growth and Health Study Research Group. Obesity and cardiovascular disease risk factors in black and white girls: the NHLBI Growth and Health Study. Am J Public Health. 1992;82:1613–1620
  20. Kimm SYS, Barton BA, Obarzanek E, McMahon RP, Sabry ZI, Waclawiw MA, et al. Racial divergence in adiposity during adolescence: the NHLBI Growth and Health Study. Pediatrics 2001;107. Available at: http://www.pediatrics.org/cgi/content/full/103/3/e34. Accessed October 18, 2006.
  21. Striegel-Moore RH, Dohm FA, Kraemer HC, Taylor CB, Daniels S, Crawford PB, et al. Eating disorders in white and black women. Am J Psychiatry. 2003;160:1326–1331
  22. Gillum RF, Liu KC. Coronary heart disease mortality in United States Blacks, 1940-1978: trends and unanswered questions. Am Heart J. 1984;108:653–657
  23. Callaway CW, Chumlea WC, Bouchard C, Himes JH, Lohman TG, Martin AD. Circumferences. In:  Lohman TG,  Roche AF,  Martorell R editor. Anthropometric standardization reference manual. Champaign, IL: Human Kinetics; 1988;p. 41–42
  24. National Heart, Lung, and Blood Institute, National Institutes of Health. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults—the evidence report. Obes Res. 1998;6:54S
  25. Morrison JA, Guo SS, Specker B, Chumlea WC, Yanovski SZ, Yanovski JA. Assessing the body composition of black and white girls in field studies, 6 to 17 years of age. Am J Hum Biol. 2001;13:249–254
  26. Cameron N. The measurement of human growth. London: Croom Hehn; 1984;
  27. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004;114:555–576
  28. Bachorik P, Walker RE, Virgil DG. High-density lipoprotein cholesterol in heparin-MnC12 supernates determined with the Dow enzymic method after precipitation of Mn+2 with HCO3-. Clin Chem. 1984;30:839–842
  29. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499–502
  30. DeLong DM, DeLong ER, Wood PD, Lippel K, Rifkind BM. A comparison of methods for the estimation of plasma low- and very low-density lipoprotein cholesterol (The Lipid Research Clinics Prevalence Study). JAMA. 1986;256:2372–2377
  31. National Cholesterol Education Program. Report of the Expert Panel on Blood Cholesterol in Children and Adolescents. Pediatrics. 1992;89:525–584
  32. Morrison JA, Friedman LA, Harlan WR, Harlan LC, Barton BA, Schreiber GB, et al. Development of the metabolic syndrome in black and white adolescent girls: a longitudinal assessment. Pediatrics. 2005;116:1178–1182
  33. Verbeke G, Molenberghs G. Linear mixed models for longitudinal data. New York: Springer; 2000;
  34. Prescott P, Brown H. Applied mixed models in medicine. Chichester, NY: Wiley; 1999;
  35. Allison PD. Survival analysis using the SAS system: a practical guide. Cary, NC: SAS Publishing; 1995;
  36. Harrell FE. Regression modeling strategies. New York: Springer-Verlag; 2001;
  37. Allison PD. Missing data. Thousand Oaks, CA: Sage; 2002;
  38. Beunckens C, Molenberghs G, Kenward MG. Direct likelihood analysis versus simple forms of imputation for missing data in randomized clinical trials. Clin Trials. 2005;2:379–386
  39. Little R, Rubin DB. Statistical analysis with missing data. New York: Wiley; 1987;
  40. Bryk AS, Raudenbush SW. Hierarchical linear models: applications and data analysis methods. Newbury Park, CA: Sage; 1992;
  41. Neter J, Kutner M, Wasserman W. Applied linear statistical models: regression, analysis of variance, and experimental designs. 3rd ed.. Homewood, IL: Irwin; 1990;
  42. Berenson GS, Srinivasan SR, Cresanta JL, Foster TA, Webber LS. Dynamic changes of serum lipoproteins in children during adolescence and sexual maturation. Am J Epidemiol. 1981;113:157–170
  43. Kwiterovich PO, Barton BA, McMahon RP, Obarzanek E, Hunsberger S, Simons-Morton D, et al. Effects of diet and sexual maturation on low-density lipoprotein cholesterol during puberty (The Dietary Intervention Study in Children (DISC)). Circulation. 1997;96:2526–2533
  44. Haas JS, Lee LB, Kaplan CP, Sonneborn D, Phillips KA, Liang SY. The association of race, socioeconomic status, and health insurance status with the prevalence of overweight among children and adolescents. Am J Public Health. 2003;93:2105–2110
  45. Rochon J, Klesges RC, Story M. Common design elements of the Girls Health Enrichment Multi-Site Study (GEMS). Ethn Dis. 2003;13:S6–S14
  46. Freedman DS, Perry G. Body composition and health status among children and adolescents. Prev Med. 2000;31:S34–S53
  47. Daniels SR, Arnett DK, Eckel RH, Gidding SS, Hayman LL, Kumanyika S, et al. Overweight in children and adolescents: pathophysiology, consequences, prevention, and treatment. Circulation. 2005;111:1999–2012
  48. Taylor RW, Jones IE, Williams SM, Goulding A. Body fat percentages measured by dual-energy X-ray absorptiometry corresponding to recently recommended body mass index cutoffs for overweight and obesity in children and adolescents aged 3-18 y. Am J Clin Nutr. 2002;76:1416–1421
  49. Zimmermann MB, Gübeli C, Püntener C, Molinari L. Detection of overweight and obesity in a national sample of 6-12-y-old Swiss children: accuracy and validity of reference values for body mass index from the US Centers for Disease Control and Prevention and the International Obesity Task Force. Am J Clin Nutr. 2004;79:838–843
  50. Katzmarzyk PT, Srinivasan SR, Chen W, Malina RM, Bouchard C, Berenson GS. Body mass index, waist circumference, and clustering of cardiovascular disease risk factors in a biracial sample of children and adolescents. Pediatrics. 2004;114:e198–e205
  51. Summerbell CD, Waters E, Edmunds LD, Brown KS, Campbell KJ. Interventions for preventing obesity in children. Cochrane Datbase Syst Rev. 2005;3:CD001871.pub2.DOI:10.1002/14651858.CD001871.pub2
  52. Luepker RV, Perry CL, McKinlay SM, Nader PR, Parcel GS, Stone EJ, et al. Outcomes of a field trial to improve children’s dietary patterns and physical activity: the Child and Adolescent Trial for Cardiovascular Health (CATCH). JAMA. 1999;275:768–776
  53. Caballero B, Clay T, Davis SM, Ethelbah B, Rock BH, Lohman T, et al. Pathways: a school-based, randomized controlled trial for the prevention of obesity in American Indian schoolchildren. Am J Clin Nutr. 2003;78:1030–1038
  54. Robinson TN. Reducing children’s television viewing to prevent obesity: a randomized controlled trial. JAMA. 1999;282:1561–1567
  55. Gortmaker SL, Peterson K, Wiecha J, Sobol AM, Dixit S, Fox MK, et al. Reducing obesity via a school-based interdisciplinary intervention among youth. Arch Pediatr Adolesc Med. 1999;153:409–418
  56. Fizgibbon ML, Stolley MR, Schiffer L, Van Horn L, Kaufer Christoffel K, Dyer A. Two-year follow-up results for Hip-Hop Health Jr: a randomized controlled trial for overweight prevention in preschool minority children. J Pediatr. 2005;146:618–625
  57. Beech BM, Klesges RC, Kumanyika K, Murray DM, Klesges L, McClanahan B, et al. Child- and parent-targeted interventions: the Memphis GEMS pilot study. Ethn Dis. 2003;13:S40–S53
  58. Robinson TN, Killen JD, Kraemer HC, Wilson DM, Matheson DM, Haskell WL. Dance and reducing television viewing to prevent weight gain in African-American girls: the Stanford GEMS pilot study. Ethn Dis. 2003;S65–S77
  59. National Institutes of Health. Ways to enhance children’s activity and nutrition (We CAN!). Available at http://wecan.nhlbi.nih.gov. Accessed October 18, 2006.
  60. Institute of Medicine. Preventing childhood obesity: health in the balance. Washington, DC: National Academies Press; 2005;
  61. Mokdad AH, Marks JS, Stroup DF, Gerberding JL. Actual causes of death in the United States, 2000. JAMA. 2004;291:1238–1245

 Supported by a grant jointly funded by the National Institute of Mental Health and the National Institute of Diabetes, Digestive, and Kidney Diseases (MH57897) and a grant from National Heart, Lung, and Blood Institute (NHLBI) (HL/DK71122), as well as NHLBI contracts HC55023-26 and cooperative agreements U01-HL-48941-44.

PII: S0022-3476(06)00926-7

doi: 10.1016/j.jpeds.2006.09.039

The Journal of Pediatrics
Volume 150, Issue 1 , Pages 18-25 , January 2007