Quality of life in children and adolescents with neurofibromatosis type I

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Graf et al at the University of Zurich assessed quality of life (QOL) and psychological adjustment in 40 children and adolescents with neurofibromatosis type I. The questionnaires were completed by both parents and children. The results show that many dimensions of QOL deviated from reference values and psychological adjustment was also impaired. The deviations correlated with family-related and illness-related factors but not with social and demographic factors. Good family relationships and cohesion were associated with a significant improvement in both QOL and psychological adjustment.