Table of Contents

Article Outline

 

Current Controversies in Pediatric Research Ethics: Proceedings Introduction S1

Douglas S. Diekema, MD, MPH, and F. Bruder Stapleton, MD, Seattle, Washington

Conducting ethical research in pediatrics: A brief historical overview and review of pediatric regulations S3

Douglas S. Diekema, MD, MPH, Seattle, Washington

Nontherapeutic research with children: The ramsey versus mccormick debate S12

Albert R. Jonsen, PhD, San Francisco, California

Appropriate compensation of pediatric research participants: Thoughts from an institute of medicine committee report S15

Bonnie W. Ramsey, MD, Seattle, Washington

Phase i research and the meaning of direct benefit S20

Lainie Ross, MD, PhD, Chicago, Illinois

A developmental approach to child assent for nontherapeutic research S25

Victoria A. Miller, PhD, and Robert M. Nelson, MD, PhD, Philadelphia, Pennsylvania

Children are not small adults: Documentation of assent for research involving children S31

David Ungar, MD, Steven Joffe, MD, and Eric Kodish, MD, Hershey, Pennsylvania, Boston, Massachusetts, and Cleveland, Ohio

Ethical issues arising from the participation of children in genetic research S34

Wylie Burke, MD, PhD, and Douglas S. Diekema, MD, MPH, Seattle, Washington

Publication Ethics: Editors’ Perspectives S39

Dimitri A. Christakis, MD, MPH, and Frederick P. Rivara, MD, MPH, Seattle, Washington

When physician-industry interactions go Awry S43

Jerome P. Kassirer, MD, Boston, Massachusetts