The Journal of Pediatrics
Volume 148, Issue 5 , Pages 623-627.e3, May 2006

Rituximab therapy for childhood-onset systemic lupus erythematosus

  • M. Willems, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • E. Haddad, MD, PhD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • P. Niaudet, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • I. Koné-Paut, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • A. Bensman, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • P. Cochat, MD, PhD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • G. Deschênes, MD, PhD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • F. Fakhouri, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • T. Leblanc, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • B. Llanas, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • C. Loirat, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • P. Pillet, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • B. Ranchin, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • R. Salomon, MD, PhD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • T. Ulinski, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • ,
  • Brigitte Bader-Meunier, MD

      Affiliations

    • Department of Pediatrics, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
    • Immuno-Allergy and Rheumatology Unit, CHU Sainte-Justine, Mother and Child University Hospital Center, Universite de Montreal, Montreal, Quebec, Canada
    • Department of Pediatric Nephrology, Hôpital Necker, Paris, France; Department of Pediatric Nephrology, Hôpital Trousseau, Paris, France
    • Department of Pediatric Nephrology, Hôpital Edouard-Herriot, Lyon, France; Department of Nephrology, Hôpital Necker, Paris, France
    • Department of Pediatric Hematology, Hôpital Saint Louis, Paris, France
    • Department of Pediatrics, Hôpital Pellegrin, Bordeaux, France
    • Department of Pediatric Nephrology, Hôpital R. Debré, Paris, France
    • Corresponding Author InformationReprint requests: Brigitte Bader-Meunier, Service de Pédiatrie générale, Hôpital de Bicêtre, 78 rue du Général Leclerc, 94276 Le Kremlin Bicêtre, France
    • ,
  • French pediatric-onset SLE study group

      Affiliations

    • Complete list of participating centers is available at www.jpeds.com

Received 18 July 2005; received in revised form 12 December 2005; accepted 20 January 2006.

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 Supported by a grant from the Association française pour le syndrome d’Evans.

PII: S0022-3476(06)00069-2

doi:10.1016/j.jpeds.2006.01.041

Refers to article:

  • Targeting B cells in the treatment of childhood-onset systemic lupus erythematosus

    Jennifer L. Huggins, Hermine I. Brunner
    The Journal of Pediatrics May 2006 (Vol. 148, Issue 5, Pages 571-573)

Refers to erratum:

  • Correction

    The Journal of Pediatrics October 2006 (Vol. 149, Issue 4, Page 586)

The Journal of Pediatrics
Volume 148, Issue 5 , Pages 623-627.e3, May 2006

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