The Journal of Pediatrics
Volume 149, Issue 1 , Pages 125-127, July 2006

Pediatric multiple sclerosis: Detection of clinically silent lesions by multimodal evoked potentials

Department of Pediatrics and Pediatric Neurology, Georg August University Goettingen, Germany.

Received 19 June 2005; received in revised form 21 October 2005; accepted 3 January 2006.

Pediatric patients with multiple sclerosis (MS) frequently do not meet MRI criteria for diagnosis because of lack of evidence of dissemination in space. We assessed the diagnostic utility of multimodal evoked potentials (EP). In 46% of 85 childhood patients with MS, spatial dissemination was detected by EP before the second clinical attack. EP may constitute an important tool for earlier diagnosis of pediatric MS.

Abbreviation:  BAEP, Brainstem auditory evoked potentials , EP, Evoked potentials , MS, Multiple sclerosis , SEP, Somatosensory evoked potentials , VEP, Visual evoked potentials

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 Supported by a grant of the Hertiestiftung (GHS 191/00).

PII: S0022-3476(06)00004-7

doi:10.1016/j.jpeds.2006.01.003

Refers to article:

  • Multiple sclerosis in children

    Lauren B. Krupp
    The Journal of Pediatrics July 2006 (Vol. 149, Issue 1, Page 8)

The Journal of Pediatrics
Volume 149, Issue 1 , Pages 125-127, July 2006

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