The Journal of Pediatrics
Volume 148, Issue 3 , Pages 332-336 , March 2006

Hearing loss in children with congenital cytomegalovirus infection born to mothers with preexisting immunity

Received 3 May 2005 ,Revised 5 August 2005 ,Accepted 1 September 2005.

References 

  1. Stagno S . Cytomegalovirus . In:  Remington JS ,  Klein JO editor. Infectious diseases of the fetus and newborn infant . 5th ed.. Philadelphia: WB Saunders; 1995;p. 389–424
  2. Demmler GJ . Infectious Diseases Society of America and Centers for Disease Control (summary of a workshop on surveillance for congenital cytomegalovirus disease) . Rev Infect Dis . 1990;13:315–329
  3. Boppana SB , Pass RF , Britt WJ , Stagno S , Alford CA . Symptomatic congenital cytomegalovirus infection (neonatal morbidity and mortality) . Pediatr Infect Dis J . 1992;11:93–99
  4. Fowler KB , Stagno S , Pass RF , Britt WJ , Boll TJ , Alford CA . The outcome of congenital cytomegalovirus infection in relation to maternal antibody status . N Engl J Med . 1992;326:663–667
  5. Ahlfors K , Ivarsson SA , Harris S . Report on a long-term study of maternal and congenital cytomegalovirus infection in Sweden. review of prospective studies available in the literature . Scand J Infect Dis . 1999;31:443–457
  6. Harris S , Ahlfors K , Ivarsson SA , Lernmark B , Svanberg L . Congenital cytomegalovirus infection and sensorineural hearing loss . Ear Hear . 1984;5:352–355
  7. Williamson WD , Demmler GJ , Percy AK , Catlin FI . Progressive hearing loss in infants with asymptomatic congenital cytomegalovirus infection . Pediatrics . 1992;90:862–866
  8. Fowler KB , McCollister FP , Dahle AJ , Boppana SB , Britt WJ , Pass RF . Progressive and fluctuating sensorineural hearing loss in children with asymptomatic congenital cytomegalovirus infection . J Pediatr . 1997;130:624–630
  9. Barbi M , Binda S , Caroppo S , Ambrosetti U , Corbetta C , Sergi P . A wider role for congenital cytomegalovirus infection in sensorineural hearing loss . Pediatr Infect Dis J . 2003;22:39–42
  10. Dahle AJ , Fowler KB , Wright JD , Boppana SB , Britt WJ , Pass RF . Longitudinal investigations of hearing disorders in children with congenital cytomegalovirus . J Am Acad Audiol . 2000;11:283–290
  11. Stagno S , Reynolds DW , Huang E-S , Thames SD , Smith RJ , Alford CA . Congenital cytomegalovirus infection (occurrence in an immune population) . N Engl J Med . 1977;296:1254–1258
  12. Fowler KB , Stagno S , Pass RF . Maternal immunity and prevention of congenital cytomegalovirus infection . JAMA . 2003;289:1008–1011
  13. Stagno S , Pass RF , Dworsky ME , Henderson RE , Moore EG , Walton PD , et al.   Congenital cytomegalovirus infection (the relative importance of primary and recurrent maternal infection) . N Engl J Med . 1982;306:945–949
  14. Ahlfors K , Ivarsson SA , Johnsson T , Svanberg L . Primary and secondary maternal cytomegalovirus infections and their relation to congenital infection. Analysis of maternal sera . Acta Paediatr Scand . 1982;71:109–113
  15. Ahlfors K , Ivarsson SA , Harris S , Svanberg L , Holmqvist R , Lernmark B , et al.   Congenital cytomegalovirus infection and disease in Sweden and the relative importance of primary and secondary maternal infections. Preliminary findings from a prospective study . Scand J Infect Dis . 1984;16:129–137
  16. Morris DJ , Sims D , Chiswick M , Das VK , Newton VE . Symptomatic congenital cytomegalovirus infection after maternal recurrent infection . Pediatr Infect Dis J . 1994;13:61–64
  17. Boppana SB , Fowler KB , Britt WJ , Stagno S , Pass RF . Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus . Pediatrics . 1999;104:55–60
  18. Gaytant MA , Rours JIJG , Steegers EAP , Galama JMD , Semmekrot BA . Congenital cytomegalovirus infection after recurrent infection (case reports and review of the literature) . Eur J Pediatr . 2003;162:248–253
  19. Stagno S , Pass RF , Cloud G , Britt WJ , Henderson RE , Walton PD , et al.   Primary Cytomegalovirus Infection in Pregnancy (Incidence, transmission to fetus and clinical outcome) . JAMA . 1986;256:1904–1908
  20. Balcarek KB , Warren W , Smith RJ , Lyon MD , Pass RF . Neonatal screening for congenital cytomegalovirus infection by detection of virus in saliva . J Infect Dis . 1993;30:1433–1436
  21. Boppana SB , Smith R , Stagno S , Britt WJ . Evaluation of a microtiter plate fluorescent antibody assay for rapid detection of human cytomegalovirus infections . J Clin Microbiol . 1992;30:721–723
  22. Bratcher DF , Bourne N , Bravo FJ , Schleiss MR , Slaoui M , Myers MG , et al.   Effect of passive antibody on congenital cytomegalovirus infection in guinea pigs . J Infect Dis . 1995;172:944–950
  23. Harrison CJ , Britt WJ , Chapman NM , Mullican J , Tracy S . Reduced congenital cytomegalovirus (CMV) infection after maternal immunization with a guinea pig CMV glycoprotein before gestational primary CMV infection in the guinea pig model . J Infect Dis . 1995;172:1212–1220
  24. Woolf NK , Harris JP , Ryan AF , Butler DM , Richman DD . Hearing loss in experimental cytomegalovirus infection of the guinea pig inner ear (prevention by systemic immunity) . Ann Otol Rhinol Laryngol . 1985;94:350–356
  25. Harris JP , Fan JT , Keithley EM . Immunologic responses in experimental cytomegalovirus labyrinthitis . Am J Otolaryngol . 1990;11:304–308
  26. Griffiths PD , Stagno S , Pass RF , Smith RJ , Alford CA . Infection with cytomegalovirus during pregnancy (specific IgM antibodies as a marker of recent primary infection) . J Infect Dis . 1982;145:647–653
  27. Stagno S , Tinker MK , Elrod C , Fuccillo DA , Cloud G , O’Beirne AJ . Immunoglobulin M antibodies detected by enzyme-linked immunosorbent assay and radioimmunoassay in the diagnosis of cytomegalovirus infections in pregnant women and newborn infants . J Clin Microbiol . 1985;21:930–935

 Supported in part by grants from the National Institutes of Health, the National Institute of Child Health and Human Development (P01 HD 10699), the National Institute of Allergy and Infectious Diseases (P01 AI43681, T32 AI052069), The National Institute on Deafness and Other Communication Disorders (R01 DC02139) and the General Clinical Research Center (M01 R00032).

PII: S0022-3476(05)00849-8

doi: 10.1016/j.jpeds.2005.09.003

The Journal of Pediatrics
Volume 148, Issue 3 , Pages 332-336 , March 2006