The Journal of Pediatrics
Volume 147, Issue 6 , Pages 843-846, December 2005

Catch-Up Growth: Testing the Hypothesis of Delayed Growth Plate Senescence in Humans

From the Department of Pediatrics, Leiden University Medical Center, Leiden, and the Department of Pediatrics, Medical Center Alkmaar, Alkmaar, Netherlands, the Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20982

Received 2 May 2005; received in revised form 1 July 2005; accepted 20 July 2005.

After a period of growth inhibition, the linear growth rate usually exceeds the normal range. This phenomenon, known as catch-up growth, was first described more than 40 years ago by Prader et al.1 It has been observed in humans and other mammals, after a wide variety of growth-inhibiting conditions, including malnutrition, Cushing syndrome, hypothyroidism, growth hormone deficiency, and many other systemic diseases.2

CA, Chronological age, BA, Bone age, SDS, Standard deviation score

 

 Supported in part by Ter Meulen Foundation, The Netherlands.

PII: S0022-3476(05)00705-5

doi:10.1016/j.jpeds.2005.07.033

The Journal of Pediatrics
Volume 147, Issue 6 , Pages 843-846, December 2005

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