The Journal of Pediatrics
Volume 134, Issue 3 , Pages 358-361, March 1999

Cysteine supplementation results in normalization of plasma taurine concentrations in children receiving home parenteral nutrition☆☆☆★

Presented at the Twentieth Clinical Congress of the American Society for Parenteral and Enteral Nutrition, Washington, DC, January 14-17, 1996.

Departments of Clinical Pharmacy and Pediatrics, the Center for Pediatric Pharmacokinetics and Therapeutics, and the Pediatric Pharmacology Research Unit at The University of Tennessee, Memphis

Received 8 May 1998; received in revised form 24 August 1998 and 2 November 1998; accepted 30 November 1998.

Abstract 

We evaluated plasma sulfur amino acid concentrations in children with short gut syndrome receiving home parenteral nutrition (n = 6). Cysteine HCl addition to solutions formulated with a pediatric amino acid product will increase plasma taurine concentrations to within the normal reference range. (J Pediatr 1999;134:358-61)

Abbreviations:  AA , Amino acid, HPN , Home parenteral nutrition, TPN , Total parenteral nutrition

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 30.00 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

☆ Funded in part by a State of Tennessee Center of Excellence grant, the Network of Pediatric Pharmacology Research Units (U01-HD-31326), and the General Clinical Research Center (M01-RR-00211) with analytical support from B Braun/McGaw, Inc, Irvine, Calif.

☆☆ Reprint requests: Richard A. Helms, PharmD, Departments of Clinical Pharmacy and Pediatrics, The University of Tennessee, 26 South Dunlap, Memphis, TN 38163-2111.

★ 0022-3476/99/$8.00 + 0  9/22/96181

PII: S0022-3476(99)70465-8

The Journal of Pediatrics
Volume 134, Issue 3 , Pages 358-361, March 1999

Article Tools

* Image Usage & Resolution